Chapter 1. Introduction to Addiction Disorders
Addiction: Substance Characteristics and Prevalence of Misuse
Neurobiological Basis of Addiction
Prevalence of Substance Misuse - Estimates for North America, Europe and Asia
North America
United States
Canada
Europe
Asia (Japan)
Incidence Estimates for Addiction Disorders in North America, Europe, and Japan
Treatment Options
Chapter 2. The Addiction Pharmacotherapy Market
Market Overview for Addiction Disorders
Market Forecasts by Therapeutic Area
Alcohol Addiction
Narcotic Addiction
Tobacco Addiction
Chapter 3. Alcohol Addiction Market
Alcohol Addiction
Acamprosate (Campral) - Merck Serono/Forest Laboratories
Disulfiram (Antabuse) - Alpharma
Naltrexone Hydrochloride
Alkermes - Reformulated Naltrexone (Vivitrol)
Pipeline Focus for Alcohol Addiction - Biotie Therapies Corp
Nalmefene
Naltrexone Depot
Alcohol Addiction - Market Insights and Future Considerations
Chapter 4. The Narcotic Addiction Market
Global Narcotics - Usage Statistics
Narcotic Addiction - The Scale of the Problem
Pharmacotherapies for Narcotic Addiction - Market Evaluation
Opioid Addiction Pharmacotherapies
Drug Substitute Therapies
Subutex/Suboxone (Buprenorphine) - Schering-Plough/Reckitt Benckiser
Suboxone Reformulation
Methadone
Drugs to Control Opioid Withdrawal Symptoms
BritLofex (Lofexidine); Opizone (Naltrexone) - Britannia Pharma/STADA
Naltrexone
Nalorex - Bristol-Myers Squibb
Opizone - Britannia
Therapeutic Switching in Addiction Markets
Outlook for Pharmacotherapeutic Markets Related to Alcohol and Narcotic Abuse
Chapter 5. Tobacco Addiction
Prevalence and Mortality Statistics
Nicotine: Mechanism of Action
Tobacco Dependence and Smoking Cessation
Smoking and Health Consequences
Healthcare Costs of Smoking Addiction
Tobacco Addiction Pharmacotherapeutics
Market Analysis of Smoking Cessation Pharmacotherapeutics
Nicotine Replacement Therapies
Nicorette/Nicotrol - McNeil Healthcare/Johnson & Johnson
Sales Estimates
NiQuitin/NicoDerm/Nicorette/Nicabate - GlaxoSmithKline
Sales Estimates
Nicotinell/Habitrol - Novartis
Sales Estimates
Neuromodulating Pharmacotherapies for Smoking Cessation
Zyban (Bupropion) - GlaxoSmithKline
Sales Estimates
Champix/Chantix (Varenicline) - Pfizer
Sales Estimates
Tobacco Addiction - Market Insights and Future Considerations
Chapter 6. Drugs in Research and Development
Addiction Disorders - Research and Development Overview
Pipeline Addiction Pharmacotherapies
Alcohol Dependence
Cocaine Dependence
Novel Late-Stage Candidates
Celtic Pharmaceuticals
Synosia Therapeutics/Roche
Cannabis Dependence
Immunotherapy Focus - InterveXion Therapeutics
Opioid Dependence
Late-Stage Development Products for Opioid Dependence
Impulse Control Disorders
Pipeline Focus - Gambling Addiction
Tobacco/Nicotine Dependence
Pipeline Focus on Immunotherapies for Tobacco Dependence
Nabi Biopharmaceuticals - NicVAX
Celtic Pharmaceuticals - TA-NIC
Smoking Cessation - A Transforming Market
Chapter 7. Market Analysis, Therapy Forecasting, and Prospect Mining
Market Analysis and Therapy Forecasting
Therapy Area Forecasts
Comparative Analysis: Addiction Pharmacotherapies
Prospect Mining
Addiction Disorder Pharmacotherapy Prospects
Therapy Area Forecasts 2016 and 2025
Chapter 8. Summary and Key Data Points on the Addiction Market
Key Data Points
Reference Sources
List of Tables
Table 1.1 Neurotransmitter Systems Associated with Addiction
Table 1.2 Drugs of Abuse and their Associations with Neurotransmitter Systems
Table 1.3 Estimated Prevalence of Substance Misuse in Europe, 2009 (000' users)
Table 1.4 Estimated Incidence for Addiction Disorders in North America, Europe and Japan, 2009 (incidence in 000s)
Table 2.1 Market Synopsis for Addiction Disorders: Current data
Table 2.2 Estimated Global Sales (US$) and Annual Growth (%) of Key Drugs to Treat Addictions, 2008-2016
Table 3.1 Physiological Consequences of the Disulfiram-Alcohol Reaction
Table 5.1 Estimated Sales (US$) and Annual Growth (%) of Smoking Cessation Therapies, 2008-2016
Table 6.1 Drugs in Development/Trials for Alcohol Dependence, 2009
Table 6.2 Drugs in Development/Trials for Cocaine Dependence, 2009
Table 6.3 Drugs in Development/Trials for Cannabis Dependence, 2009
Table 6.4 Drugs in Development/Trials for Ampetamine and Phencyclidine Dependencies, 2009
Table 6.5 Drugs in Development/Trials for Opioid Dependence, 2009
Table 6.6 Drugs in Development/Trials for Impulse Control Disorders, 2009
Table 6.7 Drugs in Development/Trials for Tobacco Addiction, 2009
Table 7.1 Estimated Global Drug Market (US$m) and Growth Rate (%) for Addiction Pharmacotherapies, 2008-2016
Table 7.2 Therapy Area Forecasts for the World Addiction Disorders Market, 2016 and 2025
List of Figures
Figure 1.1 Estimated Prevalence of Substance Misuse in United States, 2009
Figure 1.2 stimated Prevalence of Substance Misuse in Canada, 2009
Figure 1.3 Estimated Prevalence of Substance Misuse in Europe, 2009
Figure 1.4 Estimated Prevalence of Substance Misuse in Japan, 2009
Figure 2.1 Estimated Sales (US$) of Addiction Drugs Segmented by Therapeutic Area, 2008-2016
Figure 2.2 Estimated Global Sales (US$) of Leading Addiction Drugs by Therapy Area, 2009 & 2016
Figure 7.1 Comparative Analysis of Leading Addiction Pharmacotherapies, 2008-2016 (US$m)
Figure 7.2 Key Addiction Disorder Pharmacotherapy Prospects, 2009
Companies Mentioned Include:
Acrux
Alkermes
Biotie Therapies
Brookwood Pharmaceuticals
Catalyst Pharma Partners
Celtic Pharmaceuticals
Cephalon
Drug Abuse Sciences
Elbion
Eli Lilly
Forest Laboratories
GlaxoSmithKline
Impax Laboratories
InterveXion Therapeutics
J&J
Janssen-Cilag
Krele Pharma
Merck Serono
Nabi Biopharmaceuticals
Nabi Biopharmaceuticals
Pfizer
Sanofi-Aventis
Somaxon
Somaxon Pharma.
STADA
Synosia Therapeutics/Roche
Synosia Therarapeutics
Targacept
Teva Pharmaceuticals
Titan Pharmaceuticals
WorldMeds
Yaupon Therapeutics
Tim Atkinson has authored over 30 pharmaceutical market research reports and has expertise in drug discovery, drug development and drug delivery in addition to generics, parallel trade, and numerous therapeutic areas such as hormonal and metabolic disorders, oncology, and infection.
He has undertaken assignments for leading pharmaceutical companies such as Pfizer and GlaxoSmithKline, as well as for healthcare agencies and publishers such as Global Business Insights, IMS Health, and Informa Healthcare.
He worked previously as a Biomedical Scientist within the UK NHS and is a trained Medical Writer/Editor and has worked for publishers such as Thomson Science, Mosby, Churchill Livingstone and Current Science Group.
Tim founded the specialist biopharma market research firm Spectra Intelligence in 2004, which was acquired by URCH Publishing in 2009.
He holds an MSc in Health and Disease from Birkbeck College, London and he is a member of the Royal Society of Chemistry, Institute of Biology, and British Society for Immunology